Set concurrently with the events of the 2017 film on which it is based, the story places the player in the role of an unnamed soldier of Prodigium, an organization led by Dr. Henry Jekyll. Under Jekyll's command, the soldier is sent to confront the evil forces of Princess Ahmanet, pursuing her and battling the monsters under her control. The fight proves brutal and unforgiving: when a soldier is killed in action, Prodigium simply deploys a fresh recruit to continue the mission, and each new operative must track down the zombified remains of their fallen predecessor to reclaim their lost equipment before pressing on against Ahmanet's growing threat.