In the world of Gamindustri, a powerful crime syndicate known as ASIC has spread its influence across the land. When the four goddesses who watch over the nations move to confront it, they are overwhelmed and taken captive. Three years later, two loyal friends manage to free Nepgear, the goddess-in-training and younger sister of the goddess Neptune. Now Nepgear must rebuild her strength, gather allies from across the four nations, and set out to rescue her captured sisters and break ASIC's hold on the world.