In the human-and-Pokémon metropolis of Ryme City, young Tim Goodman and his wisecracking partner, the coffee-loving talking Detective Pikachu, continue their search for Tim's missing father Harry while taking on new cases. When a wave of strange Pokémon-related incidents disrupts the city and a priceless jewel is stolen during a public ceremony, the unlikely duo are pulled into a sprawling new mystery. Following clues, questioning witnesses, and teaming up with the Pokémon they meet, Tim and Pikachu work to crack the case and uncover the hidden forces stirring up chaos across Ryme City.