Set on the remote planet BG-386, the storyline of Aliens vs. Predator unfolds across three intersecting campaigns from the perspectives of a Colonial Marine rookie, an Elite Predator warrior, and a captive Xenomorph known as Specimen 6. The conflict begins when a Weyland-Yutani research expedition, led by the ruthless Karl Bishop Weyland, uncovers an ancient burial pyramid belonging to the Yautja (Predator) race. In their greed to harvest advanced technology and experiment on captured Xenomorphs, the corporation inadvertently triggers an electromagnetic pulse that knocks out the facility's security grids. This blackout allows Specimen 6 to break free, liberate the captive Xenomorph Matriarch, and overrun the colony. As the infestation spreads, a squad of United States Colonial Marines arrives to respond to the distress call, only to find themselves trapped in a desperate struggle for survival. Meanwhile, an Elite Predator named Dark is dispatched from the Yautja homeworld to avenge his fallen brethren, safeguard their sacred technology, and prevent the humans from discovering their secrets. The three distinct narrative paths cross repeatedly through the ruins, swamps, and research facilities, culminating in a final battle against Weyland's hidden synthetic forces.